Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

Prior studies have identified recurrent oncogenic mutations in colorectal adenocarcinoma and have surveyed exons of protein-coding genes for mutations in 11 affected individuals. Here we report whole-genome sequencing from nine individuals with colorectal cancer, including primary colorectal tumors...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Bass, Adam J., Lawrence, Michael S., Brace, Lear E., Ramos, Alex H., Drier, Yotam, Cibulskis, Kristian, Sougnez, Carrie, Voet, Douglas, Saksena, Gordon, Sivachenko, Andrey, Jing, Rui, Parkin, Melissa, Pugh, Trevor, Verhaak, Roel G., Stransky, Nicolas, Boutin, Adam T., Barretina, Jordi, Solit, David B., Vakiani, Evi, Lander, Eric Steven
Awduron Eraill: Massachusetts Institute of Technology. Department of Biology
Fformat: Erthygl
Iaith:en_US
Cyhoeddwyd: Nature Publishing Group 2014
Mynediad Ar-lein:http://hdl.handle.net/1721.1/84635