A Landscape of Driver Mutations in Melanoma

A Landscape of Driver Mutations in Melanoma

Despite recent insights into melanoma genetics, systematic surveys for driver mutations are challenged by an abundance of passenger mutations caused by carcinogenic UV light exposure. We developed a permutation-based framework to address this challenge, employing mutation data from intronic sequence...

Полное описание

Библиографические подробности
Главные авторы: Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicholas, Onofrio, Robert, Lander, Eric Steven
Другие авторы: Massachusetts Institute of Technology. Department of Biology
Формат: Статья
Язык:en_US
Опубликовано: Elsevier 2014
Online-ссылка:http://hdl.handle.net/1721.1/84657

Internet

http://hdl.handle.net/1721.1/84657

Схожие документы