Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay

Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay

UPF1 is a DNA/RNA helicase with essential roles in nonsense-mediated mRNA decay (NMD) and embryonic development. How UPF1 regulates target abundance and the relationship between NMD and embryogenesis are not well understood. To explore how NMD shapes the embryonic transcriptome, we integrated genome...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Hurt, Jessica A., Robertson, Alex De Jong, Burge, Christopher B
Diğer Yazarlar: Massachusetts Institute of Technology. Department of Biology
Materyal Türü: Makale
Dil:en_US
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2014
Online Erişim:http://hdl.handle.net/1721.1/84683

Internet

http://hdl.handle.net/1721.1/84683

Benzer Materyaller