Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

The muscleblind-like (Mbnl) family of RNA-binding proteins plays important roles in muscle and eye development and in myotonic dystrophy (DM), in which expanded CUG or CCUG repeats functionally deplete Mbnl proteins. We identified transcriptome-wide functional and biophysical targets of Mbnl protein...

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Bibliographic Details
Main Authors: Cody, Neal A. L., Jog, Sonali, Biancolella, Michela, Wang, Thomas T., Treacy, Daniel J., Luo, Shujun, Schroth, Gary P., Reddy, Sita, Lécuyer, Eric, Wang, Thomas, Housman, David E, Burge, Christopher B, Wang, Eric T
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/84686
https://orcid.org/0000-0001-5016-0756

Internet

http://hdl.handle.net/1721.1/84686
https://orcid.org/0000-0001-5016-0756

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