Mechanisms of protein-folding diseases at a glance

For a protein to function appropriately, it must first achieve its proper conformation and location within the crowded environment inside the cell. Multiple chaperone systems are required to fold proteins correctly. In addition, degradation pathways participate by destroying improperly folded protei...

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Bibliographic Details
Main Authors: Valastyan, Julie Suzanne, Lindquist, Susan
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Company of Biologists 2014
Online Access:http://hdl.handle.net/1721.1/84691
https://orcid.org/0000-0003-1307-882X