Fundamental differences in endoreplication in mammals and Drosophila revealed by analysis of endocycling and endomitotic cells
Throughout the plant and animal kingdoms specific cell types become polyploid, increasing their DNA content to attain a large cell size. In mammals, megakaryocytes (MKs) become polyploid before fragmenting into platelets. The mammalian trophoblast giant cells (TGCs) exploit their size to form a barr...
Main Authors: | , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
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Online Access: | http://hdl.handle.net/1721.1/84944 https://orcid.org/0000-0002-7934-111X |