Intercellular trafficking of the nuclear oncoprotein DEK

Intercellular trafficking of the nuclear oncoprotein DEK

DEK is a biochemically distinct, conserved nonhistone protein that is vital to global heterochromatin integrity. In addition, DEK can be secreted and function as a chemotactic, proinflammatory factor. Here we show that exogenous DEK can penetrate cells, translocate to the nucleus, and there carry ou...

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Bibliographic Details
Main Authors: Ploegh, Hidde, Saha, Anjan K., Kappes, Ferdinand, Mundade, Amruta, Deutzmann, Anja, Rosmarin, David M., Legendre, Maureen, Chatain, Nicolas, Al-Obaidi, Zeina, Adams, Barbara S., Ferrando-May, Elisa, Mor-Vaknin, Nirit, Markovitz, David M.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/84946
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/84946
https://orcid.org/0000-0002-1090-6071

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