Arboretum: Reconstruction and analysis of the evolutionary history of condition-specific transcriptional modules

Comparative functional genomics studies the evolution of biological processes by analyzing functional data, such as gene expression profiles, across species. A major challenge is to compare profiles collected in a complex phylogeny. Here, we present Arboretum, a novel scalable computational algorith...

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Bibliographic Details
Main Authors: Kellis, Manolis, Regev, Aviv, Roy, Sushmita, Wapinski, Ilan, Pfiffner, Jenna, French, Courtney, Socha, Amanda, Konieczka, Jay, Habib, Naomi, Thompson, Dawn
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2014
Online Access:http://hdl.handle.net/1721.1/84953
https://orcid.org/0000-0001-8567-2049