Prion formation by a yeast GLFG nucleoporin

The self-assembly of proteins into higher order structures is both central to normal biology and a dominant force in disease. Certain glutamine/asparagine (Q/N)-rich proteins in the budding yeast Saccharomyces cerevisiae assemble into self-replicating amyloid-like protein polymers, or prions, that a...

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Bibliographic Details
Main Authors: Halfmann, Randal Arthur, Wright, Jessica R., Alberti, Simon, Lindquist, Susan, Rexach, Michael
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Landes Bioscience 2014
Online Access:http://hdl.handle.net/1721.1/84962
https://orcid.org/0000-0003-1307-882X