Evolutionary principles of modular gene regulation in yeasts

Divergence in gene regulation can play a major role in evolution. Here, we used a phylogenetic framework to measure mRNA profiles in 15 yeast species from the phylum Ascomycota and reconstruct the evolution of their modular regulatory programs along a time course of growth on glucose over 300 millio...

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Bibliographic Details
Main Authors: Thompson, Dawn A., Roy, Sushmita, Chan, Michelle Mei Wah, Styczynsky, Mark P., Pfiffner, Jenna, French, Courtney, Socha, Amanda, Thielke, Anne, Napolitano, Sara, Muller, Paul, Kellis, Manolis, Konieczka, Jay, Wapinski, Ilan, Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd 2014
Online Access:http://hdl.handle.net/1721.1/84965
https://orcid.org/0000-0001-8567-2049