Evolutionary principles of modular gene regulation in yeasts
Divergence in gene regulation can play a major role in evolution. Here, we used a phylogenetic framework to measure mRNA profiles in 15 yeast species from the phylum Ascomycota and reconstruct the evolution of their modular regulatory programs along a time course of growth on glucose over 300 millio...
Main Authors: | Thompson, Dawn A., Roy, Sushmita, Chan, Michelle Mei Wah, Styczynsky, Mark P., Pfiffner, Jenna, French, Courtney, Socha, Amanda, Thielke, Anne, Napolitano, Sara, Muller, Paul, Kellis, Manolis, Konieczka, Jay, Wapinski, Ilan, Regev, Aviv |
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Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program |
Format: | Article |
Language: | en_US |
Published: |
eLife Sciences Publications, Ltd
2014
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Online Access: | http://hdl.handle.net/1721.1/84965 https://orcid.org/0000-0001-8567-2049 |
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