The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation
Human cytomegalovirus (HCMV) encodes an endoplasmic reticulum (ER)-resident transmembrane glycoprotein, US10, expressed early in the replicative cycle of HCMV as part of the same cluster that encodes the known immunoevasins US2, US3, US6, and US11. We show that US10 down-regulates cell surface expre...
Main Authors: | Park, Boyoun, Spooner, Eric, Houser, Brandy L., Strominger, Jack L., Ploegh, Hidde |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Rockefeller University Press, The
2014
|
Online Access: | http://hdl.handle.net/1721.1/84990 https://orcid.org/0000-0002-1090-6071 |
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