Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters

Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters

Cells react to their environment through gene regulatory networks. Network integrity requires minimization of undesired crosstalk between their biomolecules. Similar constraints also limit the use of regulators when building synthetic circuits for engineering applications. Here, we mapped the promot...

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Detaylı Bibliyografya
Asıl Yazarlar: Rhodius, Virgil A., Sharon, Brian D., Orlova, Ekaterina, Tabakh, Hannah, Burkhardt, David H., Clancy, Kevin, Peterson, Todd C., Gross, Carol A., Segall-Shapiro, Thomas H., Ghodasara, Amar Navin, Voigt, Christopher A.
Diğer Yazarlar: Massachusetts Institute of Technology. Department of Biological Engineering
Materyal Türü: Makale
Dil:en_US
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Online Erişim:http://hdl.handle.net/1721.1/84999
https://orcid.org/0000-0001-5409-1831
https://orcid.org/0000-0003-0844-4776
https://orcid.org/0000-0001-9364-6537

Internet

http://hdl.handle.net/1721.1/84999
https://orcid.org/0000-0001-5409-1831
https://orcid.org/0000-0003-0844-4776
https://orcid.org/0000-0001-9364-6537

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