Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells

Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells

Diabetes is caused by the loss or dysfunction of insulin-secreting β-cells in the pancreas. β-cells reduce their mass and lose insulin-producing ability in vitro, likely due to insufficient cell-cell and cell-extracellular matrix (ECM) interactions as β-cells lose their native microenvironment. Here...

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Bibliographic Details
Main Authors: Lee, Samuel, Ma, Minglin, Kim, Soo Min, Guye, Patrick, Pancoast, James R., Weiss, Ron, Lee, Richard T., Anderson, Daniel Griffith, Hammond, Paula T, Li, W.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/85010
https://orcid.org/0000-0003-0396-2443
https://orcid.org/0000-0001-5629-4798

Internet

http://hdl.handle.net/1721.1/85010
https://orcid.org/0000-0003-0396-2443
https://orcid.org/0000-0001-5629-4798

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