Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells
Diabetes is caused by the loss or dysfunction of insulin-secreting β-cells in the pancreas. β-cells reduce their mass and lose insulin-producing ability in vitro, likely due to insufficient cell-cell and cell-extracellular matrix (ECM) interactions as β-cells lose their native microenvironment. Here...
Main Authors: | Lee, Samuel, Ma, Minglin, Kim, Soo Min, Guye, Patrick, Pancoast, James R., Weiss, Ron, Lee, Richard T., Anderson, Daniel Griffith, Hammond, Paula T, Li, W. |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2014
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Online Access: | http://hdl.handle.net/1721.1/85010 https://orcid.org/0000-0003-0396-2443 https://orcid.org/0000-0001-5629-4798 |
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