The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome

Decoding of the AUA isoleucine codon in bacteria and archaea requires modification of a C in the anticodon wobble position of the isoleucine tRNA. Here, we report the crystal structure of the archaeal tRNA2Ile, which contains the modification agmatidine in its anticodon, in complex with the AUA codo...

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Bibliographic Details
Main Authors: Voorhees, Rebecca M, Mandal, Debabrata, Neubauer, Cajetan, Koehrer, Caroline, Ramakrishnan, V., Rajbhandary, Uttam L
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/85096
https://orcid.org/0000-0002-4530-5647