Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

The NKX2-1 transcription factor, a regulator of normal lung development, is the most significantly amplified gene in human lung adenocarcinoma. To study the transcriptional impact of NKX2-1 amplification, we generated an expression signature associated with NKX2-1 amplification in human lung adenoca...

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Bibliographic Details
Main Authors: Watanabe, Hideo, Francis, Joshua M., Woo, Michele S., Etemad, Banafsheh, Lin, Wenchu, Fries, Daniel F., Peng, Shouyong, Snyder, Eric, Tata, Purushothama Rao, Izzo, Francesca, Schinzel, Anna C., Cho, Jeonghee, Hammerman, Peter S., Verhaak, Roel G., Hahn, William C., Rajagopal, Jayaraj, Meyerson, Matthew L., Jacks, Tyler E
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2014
Online Access:http://hdl.handle.net/1721.1/85103
https://orcid.org/0000-0001-5785-8911

Internet

http://hdl.handle.net/1721.1/85103
https://orcid.org/0000-0001-5785-8911

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