Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

The NKX2-1 transcription factor, a regulator of normal lung development, is the most significantly amplified gene in human lung adenocarcinoma. To study the transcriptional impact of NKX2-1 amplification, we generated an expression signature associated with NKX2-1 amplification in human lung adenoca...

书目详细资料
Main Authors:	Watanabe, Hideo, Francis, Joshua M., Woo, Michele S., Etemad, Banafsheh, Lin, Wenchu, Fries, Daniel F., Peng, Shouyong, Snyder, Eric, Tata, Purushothama Rao, Izzo, Francesca, Schinzel, Anna C., Cho, Jeonghee, Hammerman, Peter S., Verhaak, Roel G., Hahn, William C., Rajagopal, Jayaraj, Meyerson, Matthew L., Jacks, Tyler E
其他作者:	Koch Institute for Integrative Cancer Research at MIT
格式:	文件
语言:	en_US
出版:	Cold Spring Harbor Laboratory Press 2014
在线阅读:	http://hdl.handle.net/1721.1/85103 https://orcid.org/0000-0001-5785-8911

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