DHODH modulates transcriptional elongation in the neural crest and melanoma

DHODH modulates transcriptional elongation in the neural crest and melanoma

Melanoma is a tumour of transformed melanocytes, which are originally derived from the embryonic neural crest. It is unknown to what extent the programs that regulate neural crest development interact with mutations in the BRAF oncogene, which is the most commonly mutated gene in human melanoma1. We...

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Bibliographic Details
Main Authors: White, Richard Mark, Cech, Jennifer N., Ratanasirintrawoot, Sutheera, Lin, Charles Y., Rahl, Peter B., Burke, Christopher J., Langdon, Erin, Tomlinson, Matthew L., Mosher, Jack, Kaufman, Charles, Chen, Frank, Long, Hannah K., Kramer, Martin, Datta, Sumon, Neuberg, Donna S., Granter, Scott, Young, Richard A., Morrison, Sean, Wheeler, Grant N., Zon, Leonard I.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/85176
https://orcid.org/0000-0001-8855-8647

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http://hdl.handle.net/1721.1/85176
https://orcid.org/0000-0001-8855-8647

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