The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

DNA damage activates a signalling network that blocks cell-cycle progression, recruits DNA repair factors and/or triggers senescence or programmed cell death. Alterations in chromatin structure are implicated in the initiation and propagation of the DNA damage response. Here we further investigate t...

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Bibliographic Details
Main Authors: Floyd, Scott R., Pacold, Michael E., Huang, Qiuying, Clarke, Scott M., Rameseder, Jonathan, Lee, Michael J., Blake, Emily J., Fydrych, Anna, Ho, Richard, Del Rosario, Amanda M., Root, David E., Carpenter, Anne E., Hahn, William C., Sabatini, David M., Chen, Clark C., White, Forest M., Bradner, James E., Yaffe, Michael B., Lam, Fred Chiu-Lai, Cannell, Ian Gordon, Bryson, Bryan D., Greenberger, Benjamin Aaron, Chen, Grace, Maffa, Amanda D.
Other Authors: Whitaker College of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/85196
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0003-3688-2378
https://orcid.org/0000-0002-9801-5037
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0001-9402-9709
https://orcid.org/0000-0001-9051-1696
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/85196
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0003-3688-2378
https://orcid.org/0000-0002-9801-5037
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0001-9402-9709
https://orcid.org/0000-0001-9051-1696
https://orcid.org/0000-0002-1446-7256

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