mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

Show other versions (1)

The mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) protein kinase promotes growth and is the target of rapamycin, a clinically useful drug that also prolongs life span in model organisms. A persistent mystery is why the phosphorylation of many bona fide mTORC1 substrates is resistant to r...

Full description

Bibliographic Details
Main Authors: Kang, Seong A., Cervantes, Christopher L., Lim, Daniel Cham-Chin, Ottina, Kathleen, Lou, Hua Jane, Gray, Nathanael S., Turk, Benjamin E., Pacold, Michael Edward, Yaffe, Michael B, Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/85198
https://orcid.org/0000-0003-3688-2378
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/85198
https://orcid.org/0000-0003-3688-2378
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0002-1446-7256

Similar Items