MicroSCALE Screening Reveals Genetic Modifiers of Therapeutic Response in Melanoma

Cell microarrays are a promising tool for performing large-scale functional genomic screening in mammalian cells at reasonable cost, but owing to technical limitations they have been restricted for use with a narrow range of cell lines and short-term assays. Here, we describe MicroSCALE (Microarrays...

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Bibliographic Details
Main Authors: Wood, Kris C., Konieczkowski, David J., Johannessen, Cory M., Boehm, Jesse S., Tamayo, Pablo, Botvinnik, Olga B., Mesirov, Jill P., Hahn, William C., Root, David E., Garraway, Levi A., Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/85203
https://orcid.org/0000-0002-1446-7256