Huntingtin Aggregation Kinetics and Their Pathological Role in a Drosophila Huntington's Disease Model
Huntington’s disease is a neurodegenerative disorder resulting from expansion of a polyglutamine tract in the Huntingtin protein. Mutant Huntingtin forms intracellular aggregates within neurons, although it is unclear whether aggregates or more soluble forms of the protein represent the pathogenic s...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Genetics Society of America, The
2014
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| Online Access: | http://hdl.handle.net/1721.1/85583 https://orcid.org/0000-0001-5576-2887 |