Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number
Genome-wide association studies (GWASs) have identified a genetic variant of moderate effect size at 6p21.1 associated with erythrocyte traits in humans. We show that this variant affects an erythroid-specific enhancer of CCND3. A Ccnd3 knockout mouse phenocopies these erythroid phenotypes, with a d...
| Autores principales: | , , , , , , , , , , , , |
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| Otros Autores: | |
| Formato: | Artículo |
| Lenguaje: | en_US |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Acceso en línea: | http://hdl.handle.net/1721.1/85590 https://orcid.org/0000-0002-7029-7415 |