Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma

Metastasis accounts for the vast majority of cancer-related deaths, yet the molecular mechanisms that drive metastatic spread remain poorly understood. Here we report that Tks5, which has been linked to the formation of proteolytic cellular protrusions known as invadopodia, undergoes an isoform swit...

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Bibliographic Details
Main Authors: Chen, Guoan, Dayton, Talya Lucia, Kim-Kiselak, Caroline, Hoersch, Sebastian, Whittaker, Charles A., Bronson, Roderick T., Beer, David G., Winslow, Monte M., Li, Carman Man-Chung, Jacks, Tyler E
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2014
Online Access:http://hdl.handle.net/1721.1/85618
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0002-7994-7963