mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

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The mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) protein kinase promotes growth and is the target of rapamycin, a clinically useful drug that also prolongs life span in model organisms. A persistent mystery is why the phosphorylation of many bona fide mTORC1 substrates is resistant to r...

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Bibliographic Details
Main Authors: Cervantes, Christopher L., Lim, Daniel Cham-Chin, Kang, Seong A., Pacold, Michael E., Lou, Hua Jane, Ottina, Kathleen, Gray, Nathanael S., Turk, Benjamin E., Yaffe, Michael B, Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/85630
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/85630
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0002-1446-7256

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