Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

Deciphering the signaling networks that underlie normal and disease processes remains a major challenge. Here, we report the discovery of signaling components involved in the Toll-like receptor (TLR) response of immune dendritic cells (DCs), including a previously unkown pathway shared across mammal...

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Bibliographic Details
Main Authors: Chevrier, Nicolas, Mertins, Philipp, Artyomov, Maxim N., Shalek, Alex K., Iannacone, Matteo, Ciaccio, Mark F., Gat-Viks, Irit, Tonti, Elena, DeGrace, Marciela M., Clauser, Karl R., Garber, Manuel, Eisenhaure, Thomas, Yosef, Nir, Robinson, Jacob, Sutton, Amy, Andersen, Mette S., Root, David E., von Andrian, Ulrich, Jones, Richard Bradley, Park, Hongkun, Carr, Steven A., Regev, Aviv, Amit, Ido, Hacohen, Nir
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/85646
https://orcid.org/0000-0001-8567-2049