Vibrio campbellii hmgA-mediated pyomelanization impairs quorum sensing, virulence, and cellular fitness

Melanization due to the inactivation of the homogentisate-1,2-dioxygenase gene (hmgA) has been demonstrated to increase stress resistance, persistence, and virulence in some bacterial species but such pigmented mutants have not been observed in pathogenic members of the Vibrio Harveyi clade. In this...

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Detalhes bibliográficos
Principais autores: Wang, Zheng, Lin, Baochuan, Mostaghim, Anahita, Rubin, Robert A., Glaser, Evan R., Mittraparp-arthorn, Pimonsri, Vuddhakul, Varaporn, Vora, Gary J., Thompson, Janelle Renee
Outros Autores: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Formato: Artigo
Idioma:en_US
Publicado em: Frontiers Research Foundation 2014
Acesso em linha:http://hdl.handle.net/1721.1/85686