Vibrio campbellii hmgA-mediated pyomelanization impairs quorum sensing, virulence, and cellular fitness

Vibrio campbellii hmgA-mediated pyomelanization impairs quorum sensing, virulence, and cellular fitness

Melanization due to the inactivation of the homogentisate-1,2-dioxygenase gene (hmgA) has been demonstrated to increase stress resistance, persistence, and virulence in some bacterial species but such pigmented mutants have not been observed in pathogenic members of the Vibrio Harveyi clade. In this...

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Bibliographic Details
Main Authors: Wang, Zheng, Lin, Baochuan, Mostaghim, Anahita, Rubin, Robert A., Glaser, Evan R., Mittraparp-arthorn, Pimonsri, Vuddhakul, Varaporn, Vora, Gary J., Thompson, Janelle Renee
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Format: Article
Language:en_US
Published: Frontiers Research Foundation 2014
Online Access:http://hdl.handle.net/1721.1/85686

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http://hdl.handle.net/1721.1/85686

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