Alternative transcription start site selection leads to large differences in translation activity in yeast
mRNA levels do not accurately predict protein levels in eukaryotic cells. To investigate contributions of 5′ untranslated regions (5′ UTRs) to mRNA-specific differences in translation, we determined the 5′ UTR boundaries of 96 yeast genes for which in vivo translational efficiency varied by 80-fold....
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Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2014
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Online Access: | http://hdl.handle.net/1721.1/85841 https://orcid.org/0000-0003-2807-9657 |