Tissue absence initiates regeneration through Follistatin-mediated inhibition of Activin signaling

Regeneration is widespread, but mechanisms that activate regeneration remain mysterious. Planarians are capable of whole-body regeneration and mount distinct molecular responses to wounds that result in tissue absence and those that do not. A major question is how these distinct responses are activa...

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Bibliographic Details
Main Authors: Gavino, Michael A., Wenemoser, Danielle, Wang, Irving E., Reddien, Peter
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2014
Online Access:http://hdl.handle.net/1721.1/85849
https://orcid.org/0000-0002-5569-333X