Creating a False Memory in the Hippocampus

Memories can be unreliable. We created a false memory in mice by optogenetically manipulating memory engram–bearing cells in the hippocampus. Dentate gyrus (DG) or CA1 neurons activated by exposure to a particular context were labeled with channelrhodopsin-2. These neurons were later optically react...

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Bibliographic Details
Main Authors: Ramirez Moreno, Steve, Liu, Xu, Lin, Pei-Ann, Suh, Junghyup, Ryan, Tomas John, Redondo, Roger L., Tonegawa, Susumu, Pignatelli di Spinazzola, Michele
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/85964
https://orcid.org/0000-0003-2839-8228
https://orcid.org/0000-0002-6697-8330
https://orcid.org/0000-0003-0121-8514