Cytochrome P450 Drives a HIF-Regulated Behavioral Response to Reoxygenation by C. elegans
Oxygen deprivation followed by reoxygenation causes pathological responses in many disorders, including ischemic stroke, heart attacks, and reperfusion injury. Key aspects of ischemia-reperfusion can be modeled by a Caenorhabditis elegans behavior, the O2-ON response, which is suppressed by hypoxic...
Main Authors: | , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2014
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Online Access: | http://hdl.handle.net/1721.1/85967 https://orcid.org/0000-0001-7092-3079 https://orcid.org/0000-0002-9964-9613 https://orcid.org/0000-0002-1693-4524 |