Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis

Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis

Intrinsic stress response pathways are frequently mobilized within tumor cells. The mediators of these adaptive mechanisms and how they contribute to carcinogenesis remain poorly understood. A striking example is heat shock factor 1 (HSF1), master transcriptional regulator of the heat shock response...

Full description

Bibliographic Details
Main Authors: Dai, Chengkai, Santagata, Sandro, Tang, Zijian, Shi, Jiayuan, Cao, Junxia, Kwon, Hyoungtae, Bronson, Roderick T., Whitesell, Luke, Lindquist, Susan
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Society for Clinical Investigation 2014
Online Access:http://hdl.handle.net/1721.1/85987
https://orcid.org/0000-0003-1307-882X

Internet

http://hdl.handle.net/1721.1/85987
https://orcid.org/0000-0003-1307-882X

Similar Items