High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome

High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome

Chromosomes must be highly compacted and organized within cells, but how this is achieved in vivo remains poorly understood. We report the use of chromosome conformation capture coupled with deep sequencing (Hi-C) to map the structure of bacterial chromosomes. Analysis of Hi-C data and polymer model...

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Bibliographic Details
Main Authors: Imakaev, Maksim Viktorovich, Le, Tung, Mirny, Leonid A, Laub, Michael T
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/86053
https://orcid.org/0000-0003-4764-8851
https://orcid.org/0000-0002-0785-5410
https://orcid.org/0000-0002-8288-7607
https://orcid.org/0000-0002-5320-2728

Internet

http://hdl.handle.net/1721.1/86053
https://orcid.org/0000-0003-4764-8851
https://orcid.org/0000-0002-0785-5410
https://orcid.org/0000-0002-8288-7607
https://orcid.org/0000-0002-5320-2728

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