High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome
Chromosomes must be highly compacted and organized within cells, but how this is achieved in vivo remains poorly understood. We report the use of chromosome conformation capture coupled with deep sequencing (Hi-C) to map the structure of bacterial chromosomes. Analysis of Hi-C data and polymer model...
Main Authors: | Imakaev, Maksim Viktorovich, Le, Tung, Mirny, Leonid A, Laub, Michael T |
---|---|
Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2014
|
Online Access: | http://hdl.handle.net/1721.1/86053 https://orcid.org/0000-0003-4764-8851 https://orcid.org/0000-0002-0785-5410 https://orcid.org/0000-0002-8288-7607 https://orcid.org/0000-0002-5320-2728 |
Similar Items
-
Modeling chromosomes: Beyond pretty pictures
by: Imakaev, Maksim Viktorovich, et al.
Published: (2017) -
Bacterial Chromosome Organization and Segregation
by: Badrinarayanan, Anjana, et al.
Published: (2018) -
Polymer models of chromosomes
by: Imakaev, Maksim (Maksim Viktorovich)
Published: (2016) -
Organization of the Mitotic Chromosome
by: Naumova, Natalia, et al.
Published: (2017) -
Higher-Order Organization Principles of Pre-translational mRNPs
by: Imakaev, Maksim Viktorovich, et al.
Published: (2020)