High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons

The formation of synapses, the specialized points of chemical communication between neurons, is a highly regulated developmental process fundamental to establishing normal brain circuitry. Perturbations of synapse formation and function causally contribute to human developmental and degenerative neu...

Полное описание

Библиографические подробности
Главные авторы: Logan, David J., Saulnier, Jessica, Lam, Daniel, Johnson, Caroline, Root, David E., Carpenter, Anne E., Sabatini, Bernardo L., Nieland, Thomas J
Другие авторы: Massachusetts Institute of Technology. Department of Biology
Формат: Статья
Язык:en_US
Опубликовано: Public Library of Science 2014
Online-ссылка:http://hdl.handle.net/1721.1/86091
https://orcid.org/0000-0003-2673-1672