Regulatory T Cells Expanded from Hiv-1-Infected Individuals Maintain Phenotype, Tcr Repertoire and Suppressive Capacity

Regulatory T Cells Expanded from Hiv-1-Infected Individuals Maintain Phenotype, Tcr Repertoire and Suppressive Capacity

While modulation of regulatory T cell (Treg) function and adoptive Treg transfer are being explored as therapeutic modalities in the context of autoimmune diseases, transplantation and cancer, their role in HIV-1 pathogenesis remains less well defined. Controversy persists regarding their beneficial...

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Bibliographic Details
Main Authors: Angin, Mathieu, Klarenbeek, Paul L., King, Melanie, Sharma, Siddhartha M., Moodley, Eshia S., Rezai, Ashley, Piechocka-Trocha, Alicja, Toth, Ildiko, Chan, Andrew T., Goulder, Philip J. R., Ndung'u, Thumbi, Kwon, Douglas, Addo, Marylyn M.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Public Library of Science 2014
Online Access:http://hdl.handle.net/1721.1/86176

Internet

http://hdl.handle.net/1721.1/86176

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