Long Signaling Cascades Tend to Attenuate Retroactivity
Signaling pathways consisting of phosphorylation/dephosphorylation cycles with no explicit feedback allow signals to propagate not only from upstream to downstream but also from downstream to upstream due to retroactivity at the interconnection between phosphorylation/dephosphorylation cycles. Howev...
Main Authors: | Ossareh, Hamid R., Ventura, Alejandra C., Merajver, Sofia D., Del Vecchio, Domitilla |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/86371 https://orcid.org/0000-0001-6472-8576 |
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