Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) κ, and Pol ζ

Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) κ, and Pol ζ

DNA synthesis across lesions during genomic replication requires concerted actions of specialized DNA polymerases in a potentially mutagenic process known as translesion synthesis. Current models suggest that translesion synthesis in mammalian cells is achieved in two sequential steps, with a Y-fami...

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Bibliographic Details
Main Authors: Wojtaszek, Jessica, Lee, Chul-Jin, D'Souza, Sanjay Victor, Minesinger, Brenda, Kim, Hyungjin, D'Andrea, Alan D., Walker, Graham C., Zhou, Pei
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Society for Biochemistry and Molecular Biology (ASBMB) 2014
Online Access:http://hdl.handle.net/1721.1/86395
https://orcid.org/0000-0001-7243-8261

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http://hdl.handle.net/1721.1/86395
https://orcid.org/0000-0001-7243-8261

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