Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

Efficient transcriptional programming promises to open new frontiers in regenerative medicine. However, mechanisms by which programming factors transform cell fate are unknown, preventing more rational selection of factors to generate desirable cell types. Three transcription factors, Ngn2, Isl1 and...

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Bibliographic Details
Main Authors: Mazzoni, Esteban O., Mahony, Shaun, Closser, Michael, Morrison, Carolyn A., Nedelec, Stephane, Williams, Damian J, An, Disi, Wichterle, Hynek, Gifford, David K.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/86926
https://orcid.org/0000-0003-1709-4034

Internet

http://hdl.handle.net/1721.1/86926
https://orcid.org/0000-0003-1709-4034

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