Multiple knockout mouse models reveal lincRNAs are required for life and brain development

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in animal models. To investigate the functional relevance of lncRNAs in various physiological conditions, we have developed a collection of 18 lncRN...

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Bibliographic Details
Main Authors: Goff, Loyal, Kellis, Manolis, Sauvageau, Martin, Lodato, Simona, Bonev, Boyan, Groff, Abigail F., Gerhardinger, Chiara, Sanchez-Gomez, Diana B., Hacisuleyman, Ezgi, Li, Eric, Spence, Matthew, Liapis, Stephen C., Mallard, William, Morse, Michael, Swerdel, Mavis R., D'Ecclessis, Michael F., Moore, Jennifer C., Lai, Venus, Gong, Guochun, Yancopoulos, George D., Frendewey, David, Hart, Ronald P., Valenzuela, David M., Arlotta, Paola, Rinn, John L.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2014
Online Access:http://hdl.handle.net/1721.1/87015

Internet

http://hdl.handle.net/1721.1/87015

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