Twofold C−H Functionalization: Palladium-Catalyzed Ortho Arylation of Anilides
The ortho arylation of anilides to form biphenyls via a twofold C−H functionalization/C−C bond-forming process is described. The oxidative coupling takes place in the presence of 5−10 mol % of Pd(OAc)[subscript 2], 10−20 mol % of DMSO, and 4−11 equiv of the aryl substrate in TFA under an oxygen atmo...
Main Authors: | , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society
2014
|
Online Access: | http://hdl.handle.net/1721.1/87074 https://orcid.org/0000-0003-3875-4775 |