Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells

Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells

Differentiation of human embryonic stem cells (hESCs) provides a unique opportunity to study the regulatory mechanisms that facilitate cellular transitions in a human context. To that end, we performed comprehensive transcriptional and epigenetic profiling of populations derived through directed dif...

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Bibliographic Details
Main Authors: Gifford, Casey A., Ziller, Michael J., Gu, Hongcang, Trapnell, Cole, Donaghey, Julie, Tsankov, Alexander, Shalek, Alex K., Kelley, David R., Shishkin, Alexander A., Issner, Robbyn, Zhang, Xiaolan, Coyne, Michael J., Fostel, Jennifer L., Holmes, Laurie, Meldrim, James C., Guttman, Mitchell, Epstein, Charles B., Park, Hongkun, Kohlbacher, Oliver, Rinn, John L., Gnirke, Andreas, Bernstein, Bradley E., Meissner, Alexander, Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/87632

Internet

http://hdl.handle.net/1721.1/87632

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