Mitigating thermal mechanical damage potential during two-photon dermal imaging

Two-photon excitation fluorescence microscopy allows in vivo high-resolution imaging of human skin structure and biochemistry with a penetration depth over 100 μm. The major damage mechanism during two-photon skin imaging is associated with the formation of cavitation at the epidermal-dermal junctio...

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Bibliographic Details
Main Authors: Masters, Barry R., So, Peter T. C., Buehler, Christof, Barry, Nicholas, Sutin, Jason D., Mantulin, William W., Gratton, Enrico
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: SPIE 2014
Online Access:http://hdl.handle.net/1721.1/87643
https://orcid.org/0000-0003-4698-6488