Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

Epithelial–mesenchymal transition (EMT) plays a critical role in the early stages of dissemination of carcinoma leading to metastatic tumors, which are responsible for over 90% of all cancer-related deaths. Current therapeutic regimens, however, have been ineffective in the cure of metastatic cancer...

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Bibliographic Details
Main Authors: Aref, Amir R., Huang, Ruby Yun-Ju, Yu, Weimiao, Chua, Kian-Ngiap, Sun, Wei, Tu, Ting-Yuan, Bai, Jing, Sim, Wen-Jing, Zervantonakis, Ioannis K., Thiery, Jean Paul, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2014
Online Access:http://hdl.handle.net/1721.1/87706
https://orcid.org/0000-0002-7232-304X