Improved Healing of Large Segmental Defects in the Rat Femur by Reverse Dynamization in the Presence of Bone Morphogenetic Protein-2

Background: Large segmental defects in bone do not heal well and present clinical challenges. This study investigated modulation of the mechanical environment as a means of improving bone healing in the presence of bone morphogenetic protein (BMP)-2. Although the influence of mechanical forces on th...

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Bibliographic Details
Main Authors: Glatt, Vaida, Miller, Micah, Ivkovic, Alan, Liu, Fangjun, Parry, Nicola, Griffin, Damian, Vrahas, Mark, Evans, Christopher H.
Other Authors: Massachusetts Institute of Technology. Division of Comparative Medicine
Format: Article
Language:en_US
Published: Journal of Bone and Joint Surgery, Inc. 2014
Online Access:http://hdl.handle.net/1721.1/88158