A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

Emerging evidence points to aberrant regulation of translation as a driver of cell transformation in cancer. Given the direct control of translation by tRNA modifications, tRNA modifying enzymes may function as regulators of cancer progression. Here, we show that a tRNA methyltransferase 9‐like (hTR...

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Bibliographic Details
Main Authors: Begley, Ulrike, Sosa, Maria Soledad, Avivar-Valderas, Alvaro, Patil, Ashish, Endres, Lauren, Estrada, Yeriel, Chan, Tsz Yan Clement, Su, Dan, Dedon, Peter C., Aguirre-Ghiso, Julio A., Begley, Thomas J.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Wiley Blackwell 2014
Online Access:http://hdl.handle.net/1721.1/88185
https://orcid.org/0000-0003-0011-3067
https://orcid.org/0000-0001-7940-3459

Internet

http://hdl.handle.net/1721.1/88185
https://orcid.org/0000-0003-0011-3067
https://orcid.org/0000-0001-7940-3459

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