KIR2DS4 Promotes HIV-1 Pathogenesis: New Evidence from Analyses of Immunogenetic Data and Natural Killer Cell Function

KIR2DS4 Promotes HIV-1 Pathogenesis: New Evidence from Analyses of Immunogenetic Data and Natural Killer Cell Function

Background: KIR2DS4 gene variants encode full-length and truncated protein products, with only the former serving as membrane-bound receptors to activate natural killer (NK) cells. We have previously shown that full-length KIR2DS4 was associated with relatively high viral load and accelerated hetero...

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Bibliographic Details
Main Authors: Merino, Aimee M., Dugast, Anne-Sophie, Wilson, Craig M., Goepfert, Paul A., Alter, Galit, Kaslow, Richard A., Tang, Jianming
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2014
Online Access:http://hdl.handle.net/1721.1/88195
https://orcid.org/0000-0003-1570-9445

Internet

http://hdl.handle.net/1721.1/88195
https://orcid.org/0000-0003-1570-9445

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