The benefits of selecting phenotype-specific variants for applications of mixed models in genomics

Applications of linear mixed models (LMMs) to problems in genomics include phenotype prediction, correction for confounding in genome-wide association studies, estimation of narrow sense heritability, and testing sets of variants (e.g., rare variants) for association. In each of these applications,...

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Xehetasun bibliografikoak
Egile Nagusiak: Lippert, Christoph, Quon, Gerald, Kang, Eun Yong, Kadie, Carl M., Listgarten, Jennifer, Heckerman, David
Beste egile batzuk: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Formatua: Artikulua
Hizkuntza:en_US
Argitaratua: Nature Publishing Group 2014
Sarrera elektronikoa:http://hdl.handle.net/1721.1/88234
https://orcid.org/0000-0002-1716-0153