DNA-binding specificity changes in the evolution of forkhead transcription factors

The evolution of transcriptional regulatory networks entails the expansion and diversification of transcription factor (TF) families. The forkhead family of TFs, defined by a highly conserved winged helix DNA-binding domain (DBD), has diverged into dozens of subfamilies in animals, fungi, and relate...

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Bibliographic Details
Main Authors: Nakagawa, So, Gisselbrecht, Stephen S., Rogers, Julia M., Hartl, Daniel L., Bulyk, Martha L.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/88252